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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF22
All Species:
25.45
Human Site:
T374
Identified Species:
56
UniProt:
Q14807
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14807
NP_015556.1
665
73262
T374
E
V
I
N
R
P
F
T
N
E
S
L
Q
P
H
Chimpanzee
Pan troglodytes
XP_510910
679
74714
T374
E
V
I
N
R
P
F
T
N
E
S
L
Q
P
H
Rhesus Macaque
Macaca mulatta
XP_001104365
657
72278
T363
E
V
I
N
R
P
F
T
N
E
S
L
Q
P
H
Dog
Lupus familis
XP_547058
651
71817
T357
E
V
I
N
R
P
F
T
N
E
S
L
Q
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3V300
660
73171
T369
E
V
I
N
R
P
F
T
N
E
S
L
Q
P
H
Rat
Rattus norvegicus
Q5I0E8
657
73037
T366
E
V
I
N
R
P
F
T
N
E
S
L
Q
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7ZYL5
650
73149
S365
Q
I
I
N
K
P
F
S
R
E
T
T
Q
T
V
Zebra Danio
Brachydanio rerio
A8WFU8
634
70574
V351
Q
I
V
N
R
P
F
V
R
E
T
V
L
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P46867
784
88189
K350
S
I
Q
N
Q
P
I
K
N
E
D
P
Q
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P46873
699
78760
D424
E
R
A
N
A
N
L
D
N
L
N
P
E
E
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LPC6
894
98404
I408
K
V
E
N
M
L
K
I
K
E
E
F
D
Y
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
94.8
90
N.A.
81.3
81
N.A.
N.A.
N.A.
52.3
50.9
N.A.
29.2
N.A.
28.1
N.A.
Protein Similarity:
100
97.5
96.2
93
N.A.
88.7
88.8
N.A.
N.A.
N.A.
69.3
66.1
N.A.
46.1
N.A.
45.7
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
N.A.
40
33.3
N.A.
33.3
N.A.
20
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
N.A.
73.3
66.6
N.A.
46.6
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
42.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
0
0
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
0
10
10
0
% D
% Glu:
64
0
10
0
0
0
0
0
0
91
10
0
10
10
0
% E
% Phe:
0
0
0
0
0
0
73
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
46
% H
% Ile:
0
28
64
0
0
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
10
10
10
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
10
10
0
0
10
0
55
10
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
100
0
10
0
0
73
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
82
0
0
0
0
0
19
0
46
19
% P
% Gln:
19
0
10
0
10
0
0
0
0
0
0
0
73
0
0
% Q
% Arg:
0
10
0
0
64
0
0
0
19
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
10
0
0
55
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
55
0
0
19
10
0
10
0
% T
% Val:
0
64
10
0
0
0
0
10
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _